Angela Santoni is Emeritus Professor of Immunology and Immunopathology at the Sapienza University of Rome, and Scientific Director of the Pasteur Institute-Italia.

She served as Head of the Department of Molecular Medicine, President of Master Course in Medical Biotechnologies and Coordinator of the PhD program in Immunology and Immunopathology. She was President of the International Society of Natural Immunity (SNI), of the Italian Society of Immunology, Clinical Immunology and Allergology (SIICA), member of IUIS Council and Italian representative of GAVI. She is member of the Academia Europaea the European Molecular Biology Organization (EMBO), and of AAI.

Her research provided relevant contributions on several aspects of NK cell biology and in particular on the signaling events underlying NK cell migration and effector functions; on the molecular mechanisms governing NK activating stress ligand expression; on NK cell immunosurveillance against senescent tumor cells as documented of the over 400 publications on peer-reviewed scientific journals.